Mandsaur do not have any Airport. The two nearest Airports are Udaipur and Indore. The Udaipur Airport is around 180 k.m in north-west and Indore Airport is around 210 k.m in South from mandsaur.
Mandsaur has its Railway station but nearest railway junctions are at Shamgargh and Ratlam where all long distance trains stops.
Mandsaur is well connected with roads. Nearby Neemuch district is about 50 KM and Ratlam district is 85 KM , connected with Mhow-Neemuch Highway road. It is also connected the Rajasthan State border via Pratapgarh which is about 25KM away.